Short answer: The Barn ($25K) supports 10 employees and is the best mid-game automation property. The Docks Warehouse ($50K) supports 12 employees and is the endgame automation hub. Each property needs a different layout: Barn uses a 2-floor vertical chain, Warehouse uses a horizontal U-shape. Cocaine 8-mix at the Warehouse yields $305 net per unit with full automation.
Barn vs Warehouse Layout Comparison

Barn Setup (10 Employees)

The Barn is the first property where full automation becomes viable. Buy it from Ray's Realty for $25,000 once you reach Dealer rank.

Optimal Employee Allocation:

ZoneEmployeesTask
Ground floor - south1 Botanist5 pots growing base strain
Ground floor - center2 Chemist4 Mixing Stations (daisy chain)
Ground floor - north3 HandlerShelf restocking + inter-zone moves
Upper floor1 Handler + 1 PackerOutput bagging + loading bay
Utility1 Botanist + 1 HandlerDrying rack management

Layout Blueprint for Meth 4-Mix:

  1. Place 4 shelves near the ground floor loading bay. Whitelist 2 ingredients per shelf.
  2. Set 4 Mixing Stations in a straight line along the center wall. Station 1 output to Station 2, and so on.
  3. Run a Handler route: Loading bay -> each shelf. Whitelist by ingredient type.
  4. Run a second Handler route: Station 4 output -> stairwell box.
  5. On the upper floor: Packer bags from the stairwell box. Handler moves bags to upper loading bay.

The Barn's 2-floor layout introduces a common failure: Handlers get stuck on stairs with large loads. Keep stairwell boxes small (1 shelf, not a rack) and limit each Handler to 4 routes max instead of 6 inside the Barn.

Docks Warehouse Setup (12 Employees)

The Docks Warehouse ($50,000, Hoodlum V rank unlock, 6PM-6AM access) is the largest automation property before the Manor.

Optimal Employee Allocation:

ZoneEmployeesTask
Main floor - east2 Botanist10 pots of coca base
Main floor - center4 Chemist8 Mixing Stations (two 4-chains)
Main floor - west4 HandlerFull logistics coverage
Loading bay2 PackerDual output bagging

Layout Blueprint for Cocaine 8-Mix:

  1. Place 6 shelves along the east wall, 3 per side. Whitelist ingredients for 8-mix: OG Kush base + Battery + Horse Semen + Mega Bean + Cuke + Paracetamol + Gasoline + Motor Oil.
  2. Set 8 Mixing Stations in two parallel 4-station chains. Chain A processes ingredients 1-4, Chain B processes 5-8.
  3. Use clipboard to merge Chain B output into Chain A's final station for the complete 8-mix.
  4. Two Packer stations at the west loading bay, each bagging different product sizes ($50 and $100 bags).
  5. Three Handlers on routes: Loading bay <-> Shelves, Shelves <-> Stations, Stations <-> Packer.
MetricBarn (Meth 4-mix, approx.)Warehouse (Coke 8-mix, approx.)
Setup cost$25K property + $5K equipment$50K property + $12K equipment
Daily employee cost~$490~$790
Units per day~120~240
Profit per unit (estimated)$100-130 (Meth)$250-350 (Cocaine)
Daily gross (estimated)$12K-$18K$60K-$85K
Days to recoup setup~2-3 days~1 day

Automation Priority Order

  1. Bungalow ($6K): Semi-auto, 4 employees. Best for starting Peddler III OG Kush production.
  2. Barn ($25K): First true automation. Upgrade at Dealer I rank when daily revenue exceeds $10K.
  3. Docks Warehouse ($50K): Endgame automation. Upgrade when you can sustain $20K/day in ingredient costs.
  4. Skip the Manor ($250K) unless you are at Kingpin rank with Cocaine 9-mix demand.

See also: Mixing Station Automation Setup for the full guide on configuring Chemist, Handler and Packer routes.