This is a curated ranking of real community-discovered strains -- not a calculator tool. Each entry includes ingredient list, sell price, profit margin, and source verification. Data cross-referenced from r/Schedule_I highest profit strains thread (May 2025), PC Gamer mixing recipes guide (April 2026), and Steam Community mixing database (January 2026).
Rank 1: God Mix (Cocaine 9-Mix)
- Base: Cocaine
- Ingredients: 9 ingredients (varies -- community has multiple 9-mix variants)
- Sell price: ~$717/unit
- Cost to make: ~$200-250
- Profit per unit: ~$467-517
- Mixing stations needed: 5
- Best for: Endgame (Kingpin rank)
- Source: r/Schedule_I "Highest Profit Strains" thread, confirmed by Schedule-1-Calculator
Rank 2: Premium Cocaine 8-Mix
- Base: Cocaine
- Ingredients: 8 ingredients
- Sell price: ~$600-650/unit
- Cost to make: ~$180-220
- Profit per unit: ~$380-470
- Mixing stations needed: 5
- Best for: Late mid-game (Dealer-Hoodlum V rank)
- Source: Steam Community mixing database, PC Gamer
Rank 3: Crystal 6-Mix
- Base: Methamphetamine
- Ingredients: Pseudo + Iodine + 4 additives
- Sell price: ~$350-400/unit
- Cost to make: ~$120-150
- Profit per unit: ~$200-280
- Mixing stations needed: 4
- Best for: Mid-game with Barn automation
- Source: Fandom Wiki Methamphetamine page, community testing
Rank 4: Grandmaster Kush (OG Kush 4-Mix)
- Base: OG Kush
- Ingredients: OG Kush + Horse Semen + Mega Bean + Gasoline
- Sell price: ~$165-175/unit
- Cost to make: ~$15-20
- Profit per unit: ~$145-160
- Mixing stations needed: 2
- Best for: Early-to-mid game (Hustler-Peddler)
- Source: Times of India "Best Strains" article, BisectHosting OG Kush combinations guide
Rank 5: Gorilla Mix (OG Kush 4-Mix)
- Base: OG Kush
- Ingredients: OG Kush + Horse Semen + Mega Bean + Donut
- Sell price: ~$150-160/unit
- Cost to make: ~$15-18
- Profit per unit: ~$132-145
- Mixing stations needed: 2
- Best for: Early game profit
- Source: Reddit community strain mixes thread
Rank 6: Ocean OG (OG Kush 4-Mix)
- Base: OG Kush
- Ingredients: OG Kush + Cuke + Motor Oil + Battery
- Sell price: ~$145-155/unit
- Cost to make: ~$12-15
- Profit per unit: ~$130-143
- Mixing stations needed: 2
- Best for: Balanced stats
- Source: Community-verified from mixing database
Rank 7: Haze Diesel (Sour Diesel 4-Mix)
- Base: Sour Diesel
- Ingredients: Sour Diesel + Gasoline + Paracetamol + Mega Bean
- Sell price: ~$160-175/unit
- Cost to make: ~$55-70
- Profit per unit: ~$90-120
- Mixing stations needed: 2
- Best for: Endgame yield
- Source: PC Gamer mixing guide, Steam Community database
Rank 8: Sweet Fruit (OG Kush 3-Mix)
- Base: OG Kush
- Ingredients: OG Kush + Banana + Cuke
- Sell price: ~$68-75/unit
- Cost to make: ~$6-8
- Profit per unit: ~$60-69
- Mixing stations needed: 2
- Best for: Mixing Mania quest completion
- Source: Times of India Mixing Mania quest guide
Rank 9: Green Crack 7-Mix (Peddler V)
- Base: Green Crack
- Ingredients: Green Crack + 6 additives
- Sell price: ~$166-180/unit
- Cost to make: ~$70-90
- Profit per unit: ~$76-110
- Mixing stations needed: 4
- Best for: Mid-game (Peddler V rank)
- Source: ScalaCube Green Crack mixes guide
Rank 10: Shroom 3-Mix
- Base: Magic Mushroom
- Ingredients: Shroom base + 2 additives
- Sell price: ~$80-100/unit
- Cost to make: ~$30-40
- Profit per unit: ~$40-70
- Mixing stations needed: 2
- Best for: New content exploration
- Source: Fandom Wiki Shrooms page, community early testing
Profit Margin Comparison Table
| Rank | Strain Name | Stations | Ingredients | Sell Price | Cost | Net Profit | Margin % |
|---|---|---|---|---|---|---|---|
| 1 | God Mix | 5 | 9 | $717 | ~$225 | ~$492 | 219% |
| 2 | Premium Coke 8-Mix | 5 | 8 | $625 | ~$200 | ~$425 | 213% |
| 3 | Crystal 6-Mix | 4 | 6 | $375 | ~$135 | ~$240 | 178% |
| 4 | Grandmaster Kush | 2 | 4 | $170 | ~$17 | ~$153 | 900% |
| 5 | Gorilla Mix | 2 | 4 | $155 | ~$16 | ~$139 | 869% |
| 6 | Ocean OG | 2 | 4 | $150 | ~$13 | ~$137 | 1,054% |
| 7 | Haze Diesel | 2 | 4 | $167 | ~$62 | ~$105 | 169% |
| 8 | Sweet Fruit | 2 | 3 | $71 | ~$7 | ~$64 | 914% |
| 9 | Green Crack 7-Mix | 4 | 7 | $173 | ~$80 | ~$93 | 116% |
| 10 | Shroom 3-Mix | 2 | 3 | $90 | ~$35 | ~$55 | 157% |
The margin percentages reveal a counter-intuitive truth: weed-based strains (Ocean OG at 1,054% margin) have WAY higher profit margins than cocaine strains (God Mix at 219%). But the absolute profit per unit is much lower. The decision comes down to: do you want high volume with low complexity (weed) or low volume with high per-unit profit (cocaine)? For automated production, weed wins on throughput. For dealer-limited setups, cocaine wins.
Practical Example
You have a Bungalow with 2 Mixing Stations and want to maximize profit with a 4-ingredient recipe.
Option A: Grandmaster Kush (OG Kush + Horse Semen + Mega Bean + Gasoline)
- 2 stations, 4 ingredients
- $170 sell price, ~$17 cost
- $153 profit per unit
- 8-12 units/day with Bungalow automation
- Daily profit: ~$1,224-1,836
Option B: Cocaine 2-mix
- 2 stations, 2 ingredients
- ~$120 sell price, ~$70 cost (coca seeds are expensive)
- $50 profit per unit
- 8-12 units/day
- Daily profit: ~$400-600
Winner: Grandmaster Kush makes roughly 3x more profit per day with the same setup. Cocaine becomes better only when you have 5+ stations (Barn/Warehouse scale).
For detailed ingredient effect reference, see the Strain Calculator guide.
Related Guides
- Best Strain By Game Stage -- decision table for early/mid/late game
- Product Quality vs Price Guide -- how quality multiplies strain value
- Bungalow 8-Step Automation Blueprint -- set up production for these strains
Community Verification & Resources
Data values may shift with patches. Cross-check against community resources before building your strategy.