Short answer: Early game (Tutorial-Hoodlum): OG Kush 4-mix with cheap additives ($120-150/unit). Mid game (Hustler-Dealer): Premium OG Kush 4-mix with Horse Semen + Mega Bean ($150-170/unit). Late game (Hoodlum V-Kingpin): Cocaine 8-9 mix ($450-717/unit). The decision depends on your available equipment, not just your rank.

This is a decision table -- not a calculator. It tells you what strain to make at each game stage based on available ingredients, equipment, and automation level. For per-unit profit numbers on each recipe, cross-reference with the recipe profit rankings.

Decision Table: What To Make At Each Stage

Game Stage Rank Best Strain Ingredients Equipment Needed Sell Price Profit Per Unit Profit Per Harvest
Tutorial Fresh Start OG Kush (raw) None (grow from seed) 1 pot, soil $28-32 ~$18-22 ~$36-44
Early I Hoodlum I Sweet Fruit (3-mix) OG Kush + Banana + Cuke 2 pots, 1 Mixing Station $68-75 ~$60-69 ~$120-138
Early II Hoodlum III-V Ocean OG (4-mix) OG Kush + Cuke + Motor Oil + Battery 2 pots, 2 Mixing Stations $145-155 ~$130-143 ~$260-286
Mid I Hustler I-II Grandmaster Kush (4-mix) OG Kush + Horse Semen + Mega Bean + Gasoline 4 pots, 2 Mixing Stations $165-175 ~$145-160 ~$580-640
Mid II Hustler III-Peddler Gorilla Mix (4-mix) OG Kush + Horse Semen + Mega Bean + Donut 4 pots, 2 Mixing Stations, Bungalow $150-160 ~$132-145 ~$528-580
Late Mid Dealer-Hoodlum V Premium Cocaine 4-mix Coca seeds + 3 premium additives 4 pots (coca), 2 Mixing Stations $200-250 ~$130-180 ~$520-720
Late I Hoodlum V Crystal 6-mix Pseudo + Iodine + 4 additives Lab oven, 4 Mixing Stations $350-400 ~$200-280 ~$800-1,120
Late II Kingpin I Cocaine 8-mix Coca + 7 premium ingredients 5 Mixing Stations, Barn $600-650 ~$380-470 ~$2,280-2,820
Endgame Kingpin III-V God Mix (Cocaine 9-mix) Coca + 8 premium ingredients 5 Mixing Stations, Warehouse $717 ~$467-517 ~$2,802-3,102

Once you know what to make, see the Bungalow workshop guide for how to automate production at each stage.

Source: Data cross-referenced from PC Gamer best mixing recipes (April 2026), Reddit highest profit strains thread (May 2025), Steam Community mixing database, and Fandom Wiki.

Where To Get Ingredients By Stage

Ingredient Early Game Mid Game Late Game Source
OG Kush seed Albert Hoover ($10) Albert Hoover Albert Hoover (Delivery) Available from start
Green Crack seed N/A (too expensive) Albert Hoover ($20) Albert Hoover Hustler rank
Sour Diesel seed N/A Albert Hoover ($35) Albert Hoover Peddler rank
Banana Gas station ($2) Gas station Gas station Always available
Cuke Gas station ($3) Gas station Gas station Always available
Battery N/A (save money) Dan's Hardware ($10) Dan's Hardware Mid-game purchase
Motor Oil N/A Gas station ($8) Gas station Mid-game
Gasoline N/A Gas station ($12) Gas station Mid-game
Horse Semen N/A Motel NPC ($20) Motel NPC Unlock at Hoodlum
Mega Bean N/A Motel NPC ($25) Motel NPC Unlock at Hoodlum
Donut N/A Convenience store ($5) Convenience store Mid-game
Paracetamol N/A Pharmacy/Supplier ($15) Supplier Mid-game
Pseudo N/A Shirley Watts ($70) Shirley Watts (Delivery) Unlock Shirley Watts
Coca seed N/A N/A Salvador Moreno ($50-80) Enforcer+ rank
Iodine N/A N/A Pharmacy ($15) Late game

Expected Profit Per Harvest

This table assumes 4 pots (mid-game) or 8 pots (late-game) and accounts for growth time.

Strain Growth Time Yield Per Harvest Sell Price Gross Profit Net Profit (After Costs) Profit Per In-Game Hour
OG Kush (raw) ~6 hrs 2 units $30 $60 ~$40 (seed+soil) ~$6.7/hr
Sweet Fruit ~6 hrs 2 units $71 $142 ~$128 ~$21.3/hr
Ocean OG ~6 hrs 2 units $150 $300 ~$274 ~$45.7/hr
Grandmaster Kush ~6 hrs 4 units $170 $680 ~$612 ~$102/hr
Cocaine 4-mix ~8 hrs 4 units $225 $900 ~$580 ~$72.5/hr
Crystal 6-mix ~4 hrs (lab) 6 units $375 $2,250 ~$1,440 ~$360/hr
Cocaine 8-mix ~8 hrs 6 units $625 $3,750 ~$2,550 ~$318.8/hr
God Mix ~8 hrs 6 units $717 $4,302 ~$2,952 ~$369/hr

Crystal 6-mix has the best profit per in-game hour ($360/hr) of any non-endgame product because meth production in the lab oven is much faster than plant growth. If you've unlocked Shirley Watts and have a lab setup, Crystal 6-mix out-earns even Cocaine 8-mix on a per-hour basis. The trade-off: meth requires constant Pseudo supply, which means more Dead Drop management.

Decision Matrix: What To Automate

Automation Level Property Best Product To Automate Why
None (manual) RV Sweet Fruit 3-mix Low ingredient count, cheap setup
Partial (3 employees) Bungalow Grandmaster Kush 4-mix 2 stations, low cost ingredients, high margin
Full (8-10 employees) Barn Cocaine 4-mix + Grandmaster Kush Dual production line; one per floor
Mega (12-16 employees) Warehouse Cocaine 8-mix Max production capacity
Max (16+ employees) Manor God Mix 9-mix Absolute maximum profit

Practical Example

You're at Hustler II with $20,000 saved. You have the Bungalow, 2 Mixing Stations, and access to Albert Hoover (Delivery unlocked) and the Motel NPC for Horse Semen and Mega Bean.

Current situation: You're making Ocean OG ($150/unit) with Cuke, Motor Oil, and Battery.

Optimization: Switch to Grandmaster Kush (OG Kush + Horse Semen + Mega Bean + Gasoline).

Why:

  • Same 2 stations, same 4 ingredients
  • Sell price jumps from $150 to $170 (13% increase)
  • Horse Semen ($20) + Mega Bean ($25) + Gasoline ($12) = $57 ingredient cost per batch
  • But you need only 1 of each per mix, and each batch creates multiple units
  • Net profit per unit increases from $137 to ~$153

Result: ~$90 extra per harvest cycle with zero additional equipment cost. Over 10 harvest cycles: ~$900 extra profit.

For the full ranked list of community-discovered strains, see Top 10 Community Custom Strains By Profit.

Community Verification & Resources

Data values may shift with patches. Cross-check against community resources before building your strategy.