Short answer: OG Kush 3-mix with horse_semen Horse semen + mega_bean Mega bean + battery Battery gives $136 profit per unit at rank Peddler III 鈥?best profit-per-effort before automation. If you have Chemists running and want max per-unit profit, build the Cocaine 9-mix at Kingpin: $717 net per unit.
Recipe Profit Per Unit

The Upgrade Path in 5 Steps

From Hoodlum to Kingpin, your recipe choices determine how fast you scale. Here is the exact sequence.

1
Hoodlum Tier 1
og_kush Og kush +banana Banana +cuke Cuke
Cost ~$6 鈫?/span> Sell ~$40 路 Profit ~$34

Buy everything from Albert and the first gas station 鈥?no alternative at this rank.

2
Hustler I鈥揑II Tier 2
og_kush Og kush +banana Banana +cuke Cuke +banana Banana
Cost ~$8 鈫?/span> Sell ~$52 路 Profit ~$44

Same ingredients as Hoodlum, one extra mix step. $2 more in ingredients, $12 more on the price tag 鈥?the easiest upgrade you'll ever make.

Peddler III Milestone
og_kush Og kush +battery Battery +horse_semen Horse semen +mega_bean Mega bean
Cost $31 鈫?/span> Sell $167 路 Net $136

Unlock horse_semen Horse semen and mega_bean Mega bean from the motel supplier. This single recipe funds your first bungalow. The biggest mid-game power spike.

4
Dealer I鈥揑I Tier 4
meth Meth +meth Meth
Cost $18 鈫?/span> Sell $145 路 Net $127

Transition from weed to meth Meth . Meth 4-mix: Chemists process 15% faster 鈥?this is your scaling inflection point.

5
Kingpin Endgame
cocaine Cocaine +9-mix
Cost $38 鈫?/span> Sell $755 路 Net $717

Cocaine 9-mix: banana Banana 鈫?motor_oil Motor oil 鈫?cuke Cuke 鈫?paracetamol Paracetamol 鈫?gasoline Gasoline 鈫?cuke Cuke 鈫?battery Battery 鈫?horse_semen Horse semen 鈫?mega_bean Mega bean . Setup ~$40,000. Sell price per unit: $755 (verified by community testing).

The Recipe That Changes Your Income Curve

If you hit Peddler III and are still running 4-step mixes for $40 profit, you are missing the single biggest mid-game money printer.

1xog_kushOg kush
+
1xbatteryBattery
+
1xhorse_semenHorse semen
+
1xmega_beanMega bean
→
1xog_kushOg kush
Cost: $31 鈫?Sell: $167 鈫?5.4x return. Two daisychained mixing stations. No special unlocks beyond Peddler III.
Why most players miss this. horse_semen Horse semen is not sold by a named supplier. It comes from a random NPC at the motel. The game does not put it on your map. You have to check every room or wait for a dealer to offer it.
Better than the alternative. Compare to Green Crack 6-mix at the same rank ($98 net) 鈥?this recipe wins by 38% more profit with half the mixing steps.

Full Profit Reference

DrugBest MixCostSellNetRankStations
og_kush Og kush3-mix (Battery/Horse/Mega)$31$167$136Peddler III2
og_kush Og kush8-mix$28$186$158Dealer I4
meth Meth4-mix$18$145$127Hustler II2
meth Meth8-mix$38$343$305Dealer II4
cocaine Cocaine9-mix$38$755$717Kingpin5
green_crack Green crack8-mix$24$148$124Dealer I4

The real bottleneck. The ingredient cost gap between a Peddler III OG Kush 3-mix and a Kingpin Cocaine 9-mix is only $7. The sell price gap is $588. It is never ingredient cost 鈥?it is production speed, station count, and automation.

Community Verification & Resources

Recipe values shift with every patch. The data above reflects v0.4 (April 2026). Before building a production line around a specific recipe, cross-check against:

Schedule 1 Calculator Real-time ingredient chain with cost and sell price Complete Mixing Database Tested recipes for all substances in v0.4 PC Gamer Recipe Guide Community-discovered recipes updated after each patch